Chiral Columns

Protein-based Chiral HPLC Columns

CHIRALPAK®AGP

Product name Product type Internal
Diameter (mm)
Length (mm) Particle size (µm) P/N
CHIRALPAK®AGP Analytical column 4 50 5 30712
Analytical column 4 100 5 30713
Analytical column 4 150 5 30714
Analytical column 3 50 5 30782
Analytical column 3 100 5 30783
Analytical column 3 150 5 30784
Analytical column 2 50 5 30792
Analytical column 2 100 5 30793
Analytical column 2 150 5 30794
Semi-prep 10 100 5 30733
Semi-prep 10 150 5 30734
Guard cartridge ( x 2 ) 2 10 5 30791
Guard cartridge ( x 2 ) 3 10 5 30781
Guard cartridge ( x 2 ) 4 10 5 30711
  Guard cartridge holder ( for AGP/CBH/HSA)     - 00081

CHIRALPAK®CBH

Product name Product type Internal
Diameter (mm)
Length (mm) Particle size (µm) P/N
CHIRALPAK®CBH Analytical column 4 50 5 33712
Analytical column 4 100 5 33713
Analytical column 4 150 5 33714
Analytical column 3 50 5 33782
Analytical column 3 100 5 33783
Analytical column 3 150 5 33784
Analytical column 2 50 5 33792
Analytical column 2 100 5 33793
Analytical column 2 150 5 33794
Semi-prep 10 100 5 33733
Semi-prep 10 150 5 33734
Guard cartridge ( x 2 ) 2 10 5 33791
Guard cartridge ( x 2 ) 3 10 5 33781
Guard cartridge ( x 2 ) 4 10 5 33711
  Guard cartridge holder ( for AGP/CBH/HSA)     - 00081

CHIRALPAK®HSA

Product name Product type Internal
Diameter (mm)
Length (mm) Particle size (µm) P/N
CHIRALPAK®HSA Analytical column 4 50 5 34712
Analytical column 4 100 5 34713
Analytical column 4 150 5 34714
Analytical column 3 50 5 34782
Analytical column 3 100 5 34783
Analytical column 3 150 5 34784
Analytical column 2 50 5 34792
Analytical column 2 100 5 34793
Analytical column 2 150 5 34794
Semi-prep 10 100 5 34733
Semi-prep 10 150 5 34734
Guard cartridge ( x 2 ) 2 10 5 34791
Guard cartridge ( x 2 ) 3 10 5 34781
Guard cartridge ( x 2 ) 4 10 5 34711
  Guard cartridge holder ( for AGP/CBH/HSA)     - 00081

Feature

CHIRALPAK®AGP has extremely broad applicability for the separation of chiral drugs.

Basic compounds : CHIRALPAK®AGP、CHIRALPAK®CBH

Acids, Non-protolytic compounds : CHIRALPAK®AGP、CHIRALPAK®HSA

  • CHIRALPAK®AGP has extremely broad applicability for the separation of chiral drugs.
  • The protein-based columns function entirely in the reversed-phase chromatographic mode, using buffers with low organic modifier content and at moderate pH values.
  • Possibility to dynamically improve enantioseparation.

CHIRALPAK AGP® has extremely broad applicability for the separation of chiral drugs.

  • The chiral selector is alpha1-acid glycoprotein (AGP). This very stable protein is immobilized onto spherical 5 micrometer silica particles.
    The CHIRALPAK®AGP column separates enantiomers of an extremely broad range of drug compounds.
    • Amine (primary, secondary, and tertiary)
    • Acids (strong and weak)
    • Nonprotolytes (amides, esters, alchohols, sulfoxides, etc.)

CHIRALPAK CBH

  • The chiral selector is Cellobiohydrolase (CBH). This is a stable enzyme, which has been immobilized onto 5 micrometer spherical silica particles.
  • CHIRALPAK®CBH is used for the separation of enantiomers of basic drugs from many compound classes. CHIRALPAK®CBH separates preferentially compounds containing one or more basic nitrogen's together with one or more hydrogen accepting or hydrogen donating groups (alcohol, phenol, carbonyl, amide, ether, sulphoxide, ester etc.).

CHIRALPAK HSA

  • The chiral selector is human serum albumin (HSA). The protein has been immobilized onto spherical 5 micrometer particles.
  • CHIRALPAK®HSA is especially suited for the separation of weak and strong acids, zwitterionic and nonprotolytic compounds.

Worldewide Network

Chiral Technologies Worldwide serves our customers with full technical support through our Group companies and distributors at your area.

Please visit the WEB page of our Group companies and distributor at your area.

Chiral Technologies Inc. Chiral Technologies Europe Daicel Chiral Technologies [China] Daicel Chiral Technologies [India]